Department of Chemistry, University of Arkansas, Fayetteville, AR 72701, USA.
Beilstein J Org Chem. 2013 Oct 1;9:1977-2001. doi: 10.3762/bjoc.9.234.
Amine radical cations are highly useful reactive intermediates in amine synthesis. They have displayed several modes of reactivity leading to some highly sought-after synthetic intermediates including iminium ions, α-amino radicals, and distonic ions. One appealing method to access amine radical cations is through one-electron oxidation of the corresponding amines under visible light photoredox conditions. This approach and subsequent chemistries are emerging as a powerful tool in amine synthesis. This article reviews synthetic applications of amine radical cations produced by visible light photocatalysis.
胺自由基阳离子是胺合成中非常有用的反应中间体。它们表现出几种反应模式，生成一些备受追捧的合成中间体，包括亚铵离子、α-氨基自由基和离域离子。一种有吸引力的方法是在可见光光氧化还原条件下通过单电子氧化相应的胺来获得胺自由基阳离子。这种方法和随后的化学方法正在成为胺合成中的有力工具。本文综述了可见光光催化产生的胺自由基阳离子在合成中的应用。
