胃肠道生理病理学中的肠内分泌细胞。

Enteroendocrine cells in gastrointestinal pathophysiology.

机构信息

Institute of Inflammation and Repair, Faculty of Medical and Human Sciences and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

出版信息

Curr Opin Pharmacol. 2013 Dec;13(6):941-5. doi: 10.1016/j.coph.2013.09.012. Epub 2013 Oct 24.

DOI:10.1016/j.coph.2013.09.012

PMID:24206752

Abstract

Enteroendocrine cells in the gastrointestinal tract play an important role in the regulation of appetite and digestive responses through the secretion of peptides. Their involvement in gastrointestinal diseases has been acknowledged, but relatively few studies have sought to clearly define their role in the pathogenesis or as therapeutic targets. Recent, but still limited, work has identified new roles for EEC in GI diseases.

摘要

胃肠道中的肠内分泌细胞通过分泌肽在调节食欲和消化反应方面发挥着重要作用。它们在胃肠道疾病中的作用已得到承认，但相对较少的研究试图明确它们在发病机制或作为治疗靶点中的作用。最近，但仍然有限的工作已经确定了 EEC 在胃肠道疾病中的新作用。