[从伏毛铁棒锤中提取和纯化异紫堇定]
[Extraction and purification of isocorydine from Dicranostigma leptopodum].
作者信息
Feng Yan, Yang Ai-Mei, Liu Jun-Xi, Di Duo-Long, Liu Yan-Juan, Li Min
机构信息
College of Life Science & Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
出版信息
Zhong Yao Cai. 2013 May;36(5):807-9.
OBJECTIVE
To optimize the conditions of extraction and purification of isocorydine from Dicranostigma leptopodum.
METHODS
Extraction conditions of isocorydine were selected on the basis of orthogonal experimental design, the static adsorption/desorption experiments were used to evaluate the optimum resin.
RESULTS
The optimum extraction parameters were as follows: the ratio of raw materials to solvent 1:15 (g/mL), extraction solvent 1% vitriol, the extraction three times and 1 h each time. LX28 resin exhibited higher adsorption efficiency.
CONCLUSION
Under the above optimum conditions, the extraction yield of isocorydine is 0.88%. The purity of isocorydine can reach 85.34% with a yield rate of 68.64%.
目的
优化从伏毛铁棒锤中提取和纯化异紫堇定的条件。
方法
基于正交实验设计选择异紫堇定的提取条件，采用静态吸附/解吸实验评估最佳树脂。
结果
最佳提取参数如下：原料与溶剂之比为1:15（g/mL），提取溶剂为1%硫酸，提取3次，每次1小时。LX28树脂表现出较高的吸附效率。
结论
在上述最佳条件下，异紫堇定的提取率为0.88%。异紫堇定的纯度可达85.34%，得率为68.64%。
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