Yamamoto T, Hirano A
Neuropathol Appl Neurobiol. 1986 Jan-Feb;12(1):3-9. doi: 10.1111/j.1365-2990.1986.tb00677.x.
Serial sections of the brains of two cases with Alzheimer's disease were stained with the standard Bodian, modified Bielschowsky (reformed Gros-Schultze's modification) and thioflavin S methods. The numbers of demonstrated Alzheimer's neurofibrillary tangles (NFTs) were different between the two silver stains: from 15 to 75% more NFTs were shown and more distinctly with the modified Bielschowsky stain than with the Bodian stain. Many of the NFTs in both cases were of eosinophilic and less argentophilic type. Although the NFTs were not counted, the thioflavin S stain seemed to have no apparent advantage over the modified Bielschowsky stain in the demonstration of NFTs.
对两例阿尔茨海默病患者大脑的连续切片采用标准博迪安染色法、改良 Bielschowsky 染色法（改良格罗斯 - 舒尔茨法）和硫黄素 S 染色法进行染色。两种银染色法所显示的阿尔茨海默病神经原纤维缠结（NFTs）数量有所不同：改良 Bielschowsky 染色法显示的 NFTs 比博迪安染色法多 15%至 75%，且更为清晰。两例中的许多 NFTs 均为嗜酸性且嗜银性较弱的类型。尽管未对 NFTs 进行计数，但在显示 NFTs 方面，硫黄素 S 染色法似乎并不比改良 Bielschowsky 染色法具有明显优势。
