Department of Chemistry, Simon Fraser University, V5A 1S6, Burnaby, British Columbia, Canada.
J Chem Ecol. 1996 Jan;22(1):49-59. doi: 10.1007/BF02040199.
Foliage from the pepper tree,Schinus molle L., is traditionally used in Ethiopia to "repel" house flies,Musca domestica L. The volatile extracts of pepper tree leaves were shown to have repellent and feeding-deterrent activity against house flies in a two-choice laboratory bioassay. High-performance liquid chromatographic fractionation of steam-distilled volatiles from leaves, monitored by laboratory bioassays, demonstrated that bioactivity is associated with two compounds,cis-menth-2-en-1-ol andtrans-piperitol. The absolute configuration of the latter was established as (1S,6S)-piperitol by comparison of acetyl lactate derivatives. Racemic compounds were synthesized from piperitone, and bioassays with house flies indicatedtrans-piperitol to be the most active house fly repellent.
从辣椒树 Schinus molle L. 的叶子中提取的挥发性物质，在传统上被用于埃塞俄比亚的“驱避”家蝇 Musca domestica L. 实验室内双选择生物测定实验表明，胡椒树的叶片挥发物提取物对家蝇具有驱避和拒食活性。通过实验室生物测定监测，对叶片蒸汽蒸馏挥发物进行高效液相色谱分离，结果表明生物活性与两种化合物有关，顺式-薄荷-2-烯-1-醇和反式-胡椒醇。通过比较乳酸乙酰酯衍生物，确定了后者的绝对构型为（1S,6S）-胡椒醇。从胡椒酮合成外消旋化合物，并在家蝇身上进行生物测定，结果表明反式-胡椒醇是最有效的家蝇驱避剂。
