Baek Se-Jin, Hwangbo Won, Kim Jin, Kim In-Sun
1 Department of Surgery, Korea University Anam Hospital, Seoul, Korea.
Int Surg. 2013 Oct-Dec;98(4):315-8. doi: 10.9738/INTSURG-D-13-00015.1.
Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.
孤立性结肠神经鞘瘤是罕见的胃肠道间质瘤。仅有少数病例报道。这些肿瘤在胃中的发生率高于大肠。这些梭形细胞病变与平滑肌瘤、平滑肌肉瘤及胃肠道间质瘤不同，因为肿瘤细胞具有独特的免疫表型，S-100和波形蛋白呈强弥漫阳性，同时CD117和平滑肌标志物染色阴性。我们报告一例70岁女性的结肠神经鞘瘤病例，该患者无特异性症状。经结肠镜检查及腹部计算机断层扫描，患者被诊断为升结肠黏膜下肿瘤。行腹腔镜辅助结肠楔形切除术。术后病理诊断为非常罕见的升结肠神经鞘瘤。该病例很有意思，因为结直肠神经鞘瘤极为罕见，且通过腹腔镜辅助楔形切除术进行治疗。
