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一例铋中毒伴不可逆性肾损害。

A case of bismuth intoxication with irreversible renal damage.

作者信息

Erden Abdulsamet, Karahan Samet, Bulut Kadir, Basak Mustafa, Aslan Tuncay, Cetinkaya Ali, Karagoz Hatice, Avci Deniz

机构信息

Internal Medicine Department, Kayseri Training and Research Hospital, Kayseri, Turkey.

出版信息

Int J Nephrol Renovasc Dis. 2013 Nov 7;6:241-3. doi: 10.2147/IJNRD.S54818. eCollection 2013.

DOI:10.2147/IJNRD.S54818
PMID:24232291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3825672/
Abstract

Bismuth is a chemical element symbolized as Bi and is a trivalent poor metal, which chemically resembles arsenic and antimony. Colloidal bismuth subcitrate (CBS) and bismuth subsalicylate are the bismuth salts widely used in the treatment of peptic ulcers, functional dyspepsia, and chronic gastritis. Intoxications with CBS are rare. In a few case reports, acute renal failure was described, but the literature review revealed no chronic renal failure related to CBS intoxication. In this case report we present a 21-year old female with chronic renal failure after a one year follow-up of CBS intoxication.

摘要

铋是一种化学元素，符号为Bi，是一种三价的贫金属，在化学性质上类似于砷和锑。枸橼酸铋钾（CBS）和碱式水杨酸铋是广泛用于治疗消化性溃疡、功能性消化不良和慢性胃炎的铋盐。CBS中毒很少见。在一些病例报告中，描述了急性肾衰竭，但文献综述显示没有与CBS中毒相关的慢性肾衰竭。在本病例报告中，我们介绍了一名21岁女性，在CBS中毒一年随访后出现慢性肾衰竭。

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1
A case of bismuth intoxication with irreversible renal damage.一例铋中毒伴不可逆性肾损害。
Int J Nephrol Renovasc Dis. 2013 Nov 7;6:241-3. doi: 10.2147/IJNRD.S54818. eCollection 2013.
2
Fanconi's syndrome, acute renal failure, and tonsil ulcerations after colloidal bismuth subcitrate intoxication.枸橼酸铋胶体中毒后出现范科尼综合征、急性肾衰竭及扁桃体溃疡。
Am J Kidney Dis. 2002 Mar;39(3):E18. doi: 10.1053/ajkd.2002.31429.
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Colloidal bismuth subcitrate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease.枸橼酸铋钾。对其药效学和药代动力学特性及其在消化性溃疡疾病中的治疗应用的综述。
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4
[Therapy of peptic ulcer and chronic gastritis with bismuth salts].[铋盐治疗消化性溃疡和慢性胃炎]
Z Gastroenterol. 1987 Sep;25 Suppl 4:34-40.
5
Acute renal failure after overdose of colloidal bismuth subcitrate.枸橼酸铋钾过量服用后导致的急性肾衰竭。
Pediatr Nephrol. 2005 Sep;20(9):1355-8. doi: 10.1007/s00467-005-1993-7. Epub 2005 Jun 10.
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Endocytic pathways and metabolic fate of colloidal bismuth subcitrate in human renal cells.胶体次枸橼酸铋在人肾细胞中的内吞途径和代谢命运。
Chem Biol Interact. 2024 Nov 1;403:111256. doi: 10.1016/j.cbi.2024.111256. Epub 2024 Sep 26.
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Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia. A double blind placebo controlled study.枸橼酸铋钾对非溃疡性消化不良症状及胃组织学的影响。一项双盲安慰剂对照研究。
Gut. 1990 Apr;31(4):476-80. doi: 10.1136/gut.31.4.476.
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Campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo controlled trial with colloidal bismuth subcitrate.非溃疡性消化不良患者的弯曲杆菌相关性胃炎：一项使用枸橼酸铋胶体的双盲安慰剂对照试验
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Bismuth: effects on gastritis and peptic ulcer.铋：对胃炎和消化性溃疡的影响。
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Antibacterial action of bismuth in relation to Campylobacter pyloridis colonization and gastritis.铋对幽门弯曲菌定植及胃炎的抗菌作用
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Int J Mol Sci. 2024 Jan 27;25(3):1600. doi: 10.3390/ijms25031600.
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Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table.接触重金属和元素周期表中其他化学元素所产生的临床和法医体征。
J Clin Med. 2023 Mar 29;12(7):2591. doi: 10.3390/jcm12072591.
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Effects of Bismuth Exposure on the Human Kidney-A Systematic Review.铋暴露对人体肾脏的影响——一项系统综述
Antibiotics (Basel). 2022 Dec 2;11(12):1741. doi: 10.3390/antibiotics11121741.
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Efficacy and Safety of Wei Bi Mei, a Chinese Herb Compound, as an Alternative to Bismuth for Eradication of .胃铋镁，一种中药复方，作为铋剂替代物用于根除幽门螺杆菌的疗效和安全性。 （注：原文句末不完整，推测补充了“幽门螺杆菌”使句子完整通顺，以便准确翻译）
Evid Based Complement Alternat Med. 2018 Feb 5;2018:4320219. doi: 10.1155/2018/4320219. eCollection 2018.

本文引用的文献

1
Behavioural and biochemical changes after simultaneous and post-treatment of vitamin A and D on cadmium toxicity.同时和治疗后给予维生素 A 和 D 对镉毒性的行为和生化变化。
Environ Toxicol Pharmacol. 1999 Jul;7(3):189-97. doi: 10.1016/s1382-6689(99)00013-7.
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Biochemical response to colloidal bismuth subcitrate: dose-time effect.对枸橼酸铋胶体的生化反应：剂量-时间效应
Biol Trace Elem Res. 2005 Summer;105(1-3):151-8. doi: 10.1385/BTER:105:1-3:151.
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Acute renal failure after overdose of colloidal bismuth subcitrate.枸橼酸铋钾过量服用后导致的急性肾衰竭。
Pediatr Nephrol. 2005 Sep;20(9):1355-8. doi: 10.1007/s00467-005-1993-7. Epub 2005 Jun 10.
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Bismuth biokinetics and kidney histopathology after bismuth overdose in rats.
Arch Toxicol. 2000 Sep;74(7):349-55. doi: 10.1007/s002040000150.
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Aminoaciduria and glycosuria following severe childhood lead poisoning.儿童重度铅中毒后的氨基酸尿症和糖尿症。
Pediatr Nephrol. 1998 Apr;12(3):218-21. doi: 10.1007/s004670050441.
6
Comparison of enhanced elimination of bismuth in humans after treatment with meso-2,3-dimercaptosuccinic acid and D,L-2,3-dimercaptopropane-1-sulfonic acid.用内消旋-2,3-二巯基琥珀酸和D,L-2,3-二巯基丙烷-1-磺酸治疗后人体铋的强化排泄比较。
Analyst. 1998 Jan;123(1):91-2. doi: 10.1039/a704945e.
7
Significant elimination of bismuth by haemodialysis with a new heavy-metal chelating agent.使用一种新型重金属螯合剂进行血液透析可有效清除铋。
Nephrol Dial Transplant. 1995;10(5):696-8.
8
Colloidal bismuth subcitrate. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in peptic ulcer disease.枸橼酸铋钾。对其药效学和药代动力学特性及其在消化性溃疡疾病中的治疗应用的综述。
Drugs. 1988 Aug;36(2):132-57. doi: 10.2165/00003495-198836020-00002.
9
Bismuth therapy in gastrointestinal diseases.铋剂在胃肠道疾病中的治疗作用
Gastroenterology. 1990 Sep;99(3):863-75. doi: 10.1016/0016-5085(90)90983-8.