Cadore Eduardo L, Moneo Ana B Bays, Mensat Marta Martinez, Muñoz Andrea Rozas, Casas-Herrero Alvaro, Rodriguez-Mañas Leocadio, Izquierdo Mikel
Department of Health Sciences, Public University of Navarre, Campus of Tudela Av. de Tarazona s/n, 31500, Tudela, Navarra, Spain.
Age (Dordr). 2014 Apr;36(2):801-11. doi: 10.1007/s11357-013-9599-7. Epub 2013 Nov 16.
This study investigated the effects of a multicomponent exercise intervention on muscle strength, incidence of falls and functional outcomes in frail elderly patients with dementia after long-term physical restraint, followed by 24 weeks of training cessation. Eighteen frail elderly patients with mild dementia (88.1 ± 5.1 years) performed a multicomponent exercise program, which consisted of 4 weeks of walking, balance and cognitive exercises, followed by 4 weeks of resistance exercise performed twice weekly [8-12 repetitions at 20-50 % of the one-repetition maximum (1RM)], combined with walking, balance and cognitive exercises. Before and after training, as well as after 24 weeks of training cessation, strength outcomes, Barthel Index, balance, gait ability, rise from a chair ability, dual task performance, incidence of falls and Mini-Mental State Examination were assessed. After the first 4 weeks of training, there was a significant improvement only in the balance test, whereas no additional changes were observed. However, after the second part of the training, the participants required significantly less time for the time-up-and-go test (P < 0.05), and improved the isometric hand grip, hip flexion and knee extension strength, as well as the leg press 1RM (P < 0.01). A significant reduction was also observed in the incidence of falls (P < 0.01). After 24 weeks of training cessation, abrupt decreases were observed in nearly all of the physical outcomes (P < 0.05). The exercise intervention improved strength, balance and gait ability in frail elderly patients with dementia after long-term physical restraint, and these benefits were lost after training cessation.
本研究调查了多组分运动干预对长期身体约束后患有痴呆症的体弱老年患者的肌肉力量、跌倒发生率和功能结局的影响,随后进行了24周的训练停止期观察。18名患有轻度痴呆的体弱老年患者(88.1±5.1岁)进行了一个多组分运动项目,该项目包括4周的步行、平衡和认知练习,随后是4周的阻力训练,每周进行两次[以一次重复最大值(1RM)的20 - 50%进行8 - 12次重复],并结合步行、平衡和认知练习。在训练前后以及训练停止24周后,评估了力量指标、巴氏指数、平衡能力、步态能力、从椅子上站起的能力、双重任务表现、跌倒发生率和简易精神状态检查。在训练的前4周后,仅平衡测试有显著改善,而未观察到其他变化。然而,在训练的第二阶段后,参与者在计时起立行走测试中所需时间显著减少(P < 0.05),并且等长握力、髋关节屈曲和膝关节伸展力量以及腿举1RM均有所改善(P < 0.01)。跌倒发生率也显著降低(P < 0.01)。在训练停止24周后,几乎所有身体指标均出现突然下降(P < 0.05)。运动干预改善了长期身体约束后患有痴呆症的体弱老年患者的力量、平衡和步态能力,而这些益处在训练停止后消失。