噬菌体：基因组、进化与应用。
phages: Genomes, evolution, and application.
作者信息
Klumpp Jochen, Loessner Martin J
机构信息
Institute of Food, Nutrition and Health; ETH Zurich; Zurich, Switzerland.
出版信息
Bacteriophage. 2013 Jul 1;3(3):e26861. doi: 10.4161/bact.26861. Epub 2013 Oct 24.
Abstract
is an important foodborne pathogen and the causative agent of Listeriosis, a potentially fatal infection. Several hundred bacteriophages have been described over the past decades, but only few have actually been characterized in some detail, and genome sequences are available for less than twenty of them. We here present an overview of what is currently known about phage genomics, their role in host evolution and pathogenicity, and their various applications in biotechnology and diagnostics.
摘要
是一种重要的食源性病原体，也是李斯特菌病的病原体，李斯特菌病是一种潜在的致命感染。在过去几十年里，已经描述了数百种噬菌体，但实际上只有少数几种得到了详细的表征，其中不到20种有基因组序列。我们在此概述目前关于噬菌体基因组学、它们在宿主进化和致病性中的作用以及它们在生物技术和诊断中的各种应用的已知情况。
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J Food Prot. 1992 Jan;55(1):13-17. doi: 10.4315/0362-028X-55.1.13.
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Host range and in vitro lysis of Listeria monocytogenes seafood isolates by bacteriophages.噬菌体对单核细胞增生李斯特菌海鲜分离株的宿主范围及体外裂解作用
Food Sci Technol Int. 2014 Dec;20(8):591-603. doi: 10.1177/1082013213497211. Epub 2013 Aug 1.
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Reassessment of the Listeria monocytogenes pan-genome reveals dynamic integration hotspots and mobile genetic elements as major components of the accessory genome.重新评估单核细胞增生李斯特菌全基因组揭示了动态整合热点和移动遗传元件是附属基因组的主要组成部分。
BMC Genomics. 2013 Jan 22;14:47. doi: 10.1186/1471-2164-14-47.
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Current knowledge and perspectives on biofilm formation: the case of Listeria monocytogenes.生物膜形成的现有知识和观点：以李斯特菌为例。
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