Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland.
J Virol. 2012 Dec;86(23):13099-102. doi: 10.1128/JVI.02350-12. Epub 2012 Sep 19.
Listeria monocytogenes is an important food-borne pathogen, and its bacteriophages find many uses in detection and biocontrol of its host. The novel broad-host-range virulent phage P70 has a unique morphology with an elongated capsid. Its genome sequence was determined by a hybrid sequencing strategy employing Sanger and PacBio techniques. The P70 genome contains 67,170 bp and 119 open reading frames (ORFs). Our analyses suggest that P70 represents an archetype of virus unrelated to other known Listeria bacteriophages.
李斯特菌是一种重要的食源性致病菌，其噬菌体在宿主的检测和生物防治方面有多种用途。新型广谱烈性噬菌体 P70 具有独特的长衣壳形态。其基因组序列通过采用 Sanger 和 PacBio 技术的混合测序策略确定。P70 基因组包含 67170bp 和 119 个开放阅读框（ORFs）。我们的分析表明，P70 代表了一种与其他已知李斯特菌噬菌体无关的病毒原型。
