Solanki Amrita, Bansal Shaifali, Jindal Sushil, Saxena Vivek, Shukla Uma Shankar
Department of Medicine, Peoples College of Medical Sciences and Research Centre, Bhanpur, Bhopal, Madhya Pradesh, India.
Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S167-9. doi: 10.4103/2230-8210.119560.
To investigate any possible relationship between serum thyroid stimulating hormone (TSH) with body mass index (BMI) in healthy adults.
A total of 417 subjects aged 18-60 years who volunteered to get screened for thyroid illness with serum TSH have been enrolled from November 2012 to July 2013. Patients were divided into four groups based on BMI value: Underweight (BMI <18 kg/m(2)), normal (BMI: 18-22.9 kg/m(2)), overweight (BMI: 23-24.9 kg/m(2)), and obese (BMI ≥25 kg/m(2)).
In our study we found a significant variation (P < 0.001) in TSH with increasing BMI. As the BMI increased, mean TSH in the BMI range also increased. The individuals with higher BMI had higher TSH and this trend continued from underweight to Obese. The mean TSH of underweight group was 1.6036 mIU/L, normal weight group 2.1727 mIU/L, overweight group 2.2870 mIU/L and obese group 2.6416 mIU/L.
In this study we found a significant relationship between serum TSH and BMI and mean TSH increased as BMI increased. Further large scale data from the population is required to confirm our findings.
探讨健康成年人血清促甲状腺激素（TSH）与体重指数（BMI）之间可能存在的关系。
2012年11月至2013年7月，共招募了417名年龄在18 - 60岁之间自愿接受血清TSH甲状腺疾病筛查的受试者。根据BMI值将患者分为四组：体重过轻（BMI <18 kg/m²）、正常（BMI：18 - 22.9 kg/m²）、超重（BMI：23 - 24.9 kg/m²）和肥胖（BMI≥25 kg/m²）。
在我们的研究中，我们发现随着BMI的增加，TSH存在显著变化（P < 0.001）。随着BMI的增加，BMI范围内的平均TSH也增加。BMI较高的个体TSH也较高，这种趋势从体重过轻到肥胖持续存在。体重过轻组的平均TSH为1.6036 mIU/L，正常体重组为2.1727 mIU/L，超重组为2.2870 mIU/L，肥胖组为2.6416 mIU/L。
在本研究中，我们发现血清TSH与BMI之间存在显著关系，且平均TSH随着BMI的增加而增加。需要来自人群的进一步大规模数据来证实我们的发现。
