Sami Abdul, Iftekhar Malik Faisal, Rauf Muhammad Abdur, Sher Akhter
Dr. Abdul Sami, FCPS. Department of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan.
Dr. Malik Faisal Iftekhar, FCPS. Department of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan.
Pak J Med Sci. 2018 Jul-Aug;34(4):980-983. doi: 10.12669/pjms.344.14127.
To determine the frequency of subclinical hypothyroidism in local adult obese population.
The study was conducted at Hayatabad Medical Complex, Peshawar, from March, 2017 to August, 2017. All patients aged between 18 and 60 years with BMI of more than 29kg/m were included in the study. Patients on lipid lowering drugs, with renal failure, hepatic failure and already diagnosed cases of thyroid dysfunction were excluded from the study. Thyroid functions were measured for all patients.
A total of 127 adults were included in the study in a consecutive manner. Mean age was 34.5 + 7.9 years of which 46.5% were male and 53.5% were female. Mean BMI was 32.05±2.06 kg/m. The mean serum TSH was 3.13±1.10 mIU/L and mean serum thyroxine level was 1.08±0.25ng/dl. Subclinical hypothyroidism was recorded in 15% of the study population.
Subclinical hypothyroidism is highly prevalent in our population with BMI of more than 29kg/m. Further studies are recommended on relationship between thyroid functions and BMI and its effect on cardiovascular functions.
确定当地成年肥胖人群中亚临床甲状腺功能减退症的发生率。
该研究于2017年3月至2017年8月在白沙瓦的哈亚塔巴德医疗中心进行。所有年龄在18至60岁之间、体重指数超过29kg/m的患者均纳入研究。正在服用降脂药物、患有肾衰竭、肝功能衰竭以及已确诊甲状腺功能障碍的患者被排除在研究之外。对所有患者进行甲状腺功能检测。
共有127名成年人连续纳入该研究。平均年龄为34.5±7.9岁，其中男性占46.5%，女性占53.5%。平均体重指数为32.05±2.06kg/m。血清促甲状腺激素平均水平为3.13±1.10mIU/L，血清甲状腺素平均水平为1.08±0.25ng/dl。15%的研究人群存在亚临床甲状腺功能减退症。
在体重指数超过29kg/m的人群中，亚临床甲状腺功能减退症非常普遍。建议进一步研究甲状腺功能与体重指数之间的关系及其对心血管功能的影响。
