Yamamoto Takeshi, Inoue Yuzaburo, Tomiita Minako, Oikawa Makiko, Kambe Naotomo, Arima Takayasu, Shimojo Naoki, Kohno Yoichi
a Department of Pediatrics , Graduate School of Medicine, Chiba University , Chuou-ku, Chiba City, Chiba , Japan.
b Department of Allergy and Rheumatology , Chiba Children's Hospital , Midori-ku, Chiba City, Chiba , Japan.
Mod Rheumatol. 2015;25(6):967-9. doi: 10.3109/14397595.2013.844388. Epub 2013 Oct 21.
Cutaneous polyarteritis nodosa (cutaneous PAN) is a form of necrotizing vasculitis of small- and medium-sized arteries, primarily involving the skin. In juvenile cases, cutaneous PAN is known to be frequently associated with Group A β-hemolytic Streptococcus (GAS) infections. We herein describe the first reported juvenile case of GAS-associated recurrent cutaneous PAN successfully improved with tonsillectomy. To avoid the use of steroids and immunosuppressive drugs, especially in juvenile cases, tonsillectomy is a possible treatment for GAS-associated recurrent cutaneous PAN.
皮肤型结节性多动脉炎（皮肤型PAN）是一种中小动脉的坏死性血管炎，主要累及皮肤。在青少年病例中，已知皮肤型PAN常与A组β溶血性链球菌（GAS）感染相关。我们在此报告首例经扁桃体切除成功改善的GAS相关复发性皮肤型PAN青少年病例。为避免使用类固醇和免疫抑制药物，尤其是在青少年病例中，扁桃体切除是治疗GAS相关复发性皮肤型PAN的一种可行方法。
