分支RNA的化学合成
Chemical synthesis of branched RNA.
作者信息
Kierzek R, Kopp D W, Edmonds M, Caruthers M H
出版信息
Nucleic Acids Res. 1986 Jun 25;14(12):4751-64. doi: 10.1093/nar/14.12.4751.
Abstract
A branched tetranucleotide consisting of adenosine linked 2' and 5' to guanosine and 3' to cytidine was synthesized from appropriately protected nucleoside phosphoramidites as synthons. The product was characterized enzymatically.
摘要
由适当保护的核苷亚磷酰胺作为合成子合成了一种分支四核苷酸，其由2'和5'连接到鸟苷、3'连接到胞苷的腺苷组成。该产物通过酶法进行了表征。
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