Keren Leeat, Segal Eran
Genome Biol. 2013 Nov 21;14(11):138. doi: 10.1186/gb4139.
A new study exploits the time-dependence of formaldehyde cross-linking in the commonly used chromatin immunoprecipitation (ChIP) assay to infer the on and off rates for site-specific chromatin interactions.
一项新研究利用了常用的染色质免疫沉淀(ChIP)分析中甲醛交联的时间依赖性,来推断位点特异性染色质相互作用的结合和解离速率。