Dr Ruth Chan, Research assistant professor, Rm 124021, 10/F Clinical Sciences Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, Telephone number: (852) 2632 2190, Fax number: (852) 2637 9215, Email:
J Nutr Health Aging. 2013;17(10):866-74. doi: 10.1007/s12603-013-0334-y.
Dietary patterns can be identified by a priori and a posterior approaches. Limited data have related dietary patterns with stroke risk in Chinese population. This study examined stroke risk associated with patterns identified by both approaches.
Data on 1,338 Chinese men and 1,397 Chinese women aged >= 65 years participating in a cohort study examining the risk factors for osteoporosis in Hong Kong were analyzed. Baseline dietary data were collected between 2001 and 2003 using a validated food frequency questionnaire. Adherence to a priori dietary patterns including the Mediterranean Diet Score (MDS) and the Dietary Approaches to Stop Hypertension (DASH) was assessed. Factor analysis (FA) identified three a posterior dietary patterns: "vegetables-fruits", "snacks-drinks-milk products", and "meat-fish". Data on incidence of stroke were retrieved from an official database in 2008. Cox regression was used to estimate hazard ratios (HRs) for stroke risk adjusted for potential confounders.
There were 156 incident stroke events during a median follow up of 5.7 years. A posterior dietary patterns derived by FA were not associated with risk of incident stroke in either men or women. MDS was inversely associated with risk of incident stroke [Adjusted HR=0.55 (95% CI: 0.31-0.99) of the highest level of MDS compared with the lowest level, ptrend=0.008] in men but not in women. Similar non-significant inverse association was observed between DASH accordance and stroke risk in men [Multivariate HR (95% CI) of the DASH score of >=4.5 = 0.62 (0.38-1.04) compared with the DASH score of <=4, ptrend = 0.068] but not in women.
Our findings suggest that higher MDS and possibly higher DASH scores were associated with lower stroke risk in Chinese older people in Hong Kong.
饮食模式可以通过先验和后验方法来确定。有限的数据表明饮食模式与中国人中风风险有关。本研究检验了通过这两种方法确定的饮食模式与中风风险的关系。
分析了香港骨质疏松危险因素队列研究中 1338 名男性和 1397 名 65 岁及以上的中国参与者的数据。在 2001 年至 2003 年期间，使用经过验证的食物频率问卷收集了基线饮食数据。评估了先验饮食模式（包括地中海饮食评分（MDS）和停止高血压的饮食方法（DASH））的依从性。因子分析（FA）确定了三个后验饮食模式：“蔬菜-水果”、“零食-饮料-奶制品”和“肉-鱼”。2008 年从官方数据库中检索中风发病数据。Cox 回归用于估计经潜在混杂因素调整后的中风风险的危险比（HR）。
在中位随访 5.7 年期间，发生了 156 例中风事件。通过 FA 得出的后验饮食模式与男性或女性中风风险均无关联。MDS 与中风风险呈负相关[最高 MDS 水平与最低水平相比，调整后的 HR=0.55（95% CI：0.31-0.99），ptrend=0.008]，但在女性中无统计学意义。在男性中，也观察到 DASH 一致性与中风风险之间的类似非显著负相关[DASH 评分>=4.5 与 DASH 评分<=4 相比，多变量 HR（95% CI）为 0.62（0.38-1.04），ptrend=0.068]，但在女性中无统计学意义。
我们的研究结果表明，在香港的中国老年人中，较高的 MDS 和可能较高的 DASH 评分与较低的中风风险相关。
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