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无脊椎动物中的可变免疫分子。

Variable immune molecules in invertebrates.

机构信息

Department of Comparative Physiology, Uppsala University, Norbyvägen 18A, 752 36 Uppsala, Sweden.

出版信息

J Exp Biol. 2013 Dec 1;216(Pt 23):4313-9. doi: 10.1242/jeb.085191.

DOI:10.1242/jeb.085191
PMID:24259255
Abstract

Recently it has become evident that invertebrates may mount a highly variable immune response that is dependent on which pathogen is involved. The molecular mechanisms behind this diversity are beginning to be unravelled and in several invertebrate taxa immune proteins exhibiting a broad range of diversity have been found. In some cases, evidence has been gathered suggesting that this molecular diversity translates into the ability of an affected invertebrate to mount a defence that is specifically aimed at a particular pathogen.

摘要

最近,人们已经意识到,无脊椎动物可能会产生高度可变的免疫反应,具体取决于涉及的病原体。这种多样性背后的分子机制开始被揭示,在一些无脊椎动物类群中已经发现了具有广泛多样性的免疫蛋白。在某些情况下,已经有证据表明,这种分子多样性转化为受影响的无脊椎动物产生专门针对特定病原体的防御能力。

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