Holzmann R, Shakery K
Global Medical Affairs Dermatology, Bayer Pharma AG, Berlin, Germany.
Skin Pharmacol Physiol. 2014;27 Suppl 1:3-8. doi: 10.1159/000354887. Epub 2013 Nov 13.
Acne in the adult female often presents as a chronic condition that can have a considerable negative psychological, social and emotional impact on the affected individual. Estimated prevalence rates of adult female acne vary widely according to study type. Case reports and clinical examinations estimate the prevalence of clinical acne at 10-12%, while survey estimates of physiological disease states are as high as 54%. Two subtypes of adult female acne may be defined according to time of onset: 'persistent' and 'late-onset', accounting for approximately 80 and 20% of cases, respectively. Postadolescent acne is generally mild-to-moderate in severity and presents with more inflammatory lesions and fewer comedones compared to adolescent acne. Furthermore, the impact of acne on the quality of life is often greater in adult females than in younger individuals. Despite these important differences, the key principles of acne treatment in the adult female do not differ significantly from those of other age groups. However, specific characteristics relating to the adult female should be considered when selecting a treatment regimen.
成年女性痤疮常表现为一种慢性疾病，会对患者产生相当大的负面心理、社交和情绪影响。根据研究类型的不同，成年女性痤疮的估计患病率差异很大。病例报告和临床检查估计临床痤疮的患病率为10%-12%，而对生理疾病状态的调查估计高达54%。成年女性痤疮可根据发病时间分为两种亚型：“持续性”和“迟发性”，分别约占病例的80%和20%。与青少年痤疮相比，青春期后痤疮的严重程度一般为轻度至中度，炎症性皮损更多，粉刺更少。此外，痤疮对成年女性生活质量的影响通常比年轻个体更大。尽管存在这些重要差异，但成年女性痤疮治疗的关键原则与其他年龄组并无显著不同。然而，在选择治疗方案时应考虑成年女性的特定特征。
