Department of Dermato-Oncology, University Hospital Hotel Dieu, Nantes, France.
J Eur Acad Dermatol Venereol. 2013 Sep;27(9):1063-70. doi: 10.1111/jdv.12061. Epub 2013 Jan 10.
In the adult female, acne is a chronic condition with a substantial negative psychological, social and emotional impact. Based on time of onset, two subtypes of adult female acne are recognized: 'persistent acne' is a continuation of the disease from adolescence, while 'late-onset acne' first presents in adulthood. The morphological characteristics of adult female acne are often distinct from adolescent acne. In adults, inflammatory lesions (particularly papules, pustules and nodules) are generally more prominent on the lower chin, jawline and neck, and comedones are more often closed comedones (micro cysts). Adult acne is mainly mild-to-moderate in severity and may be refractory to treatment. A holistic approach to acne therapy should be taken in adult females, which combines standard treatments with adjunctive therapy and cosmetic use. A number of factors specific to the adult female influence choice of treatment, including the predisposition of older skin to irritation, a possible slow response to treatment, a high likelihood of good adherence, whether of child-bearing age, and the psychosocial impact of the disease. Adherence to therapy should be encouraged through further patient education and a simplified regimen that is tailored to suit the individual patient's needs and lifestyle. This article reviews the specific characteristics of adult female acne, and provides recommendations for acne therapy in this patient group.
在成年女性中，痤疮是一种慢性疾病，会对她们的心理、社交和情绪产生重大负面影响。根据发病时间，可将成年女性痤疮分为两种亚型：“持续性痤疮”是青春期疾病的延续，而“迟发性痤疮”则首次出现在成年期。成年女性痤疮的形态特征通常与青少年痤疮不同。在成年人中，炎症性皮损（尤其是丘疹、脓疱和结节）通常更常见于下颌、下颌线和颈部，粉刺则更常见于闭合性粉刺（微粉刺）。成人痤疮的严重程度通常为轻至中度，可能对治疗有抗药性。在成年女性中，应采用整体方法治疗痤疮，将标准治疗与辅助治疗和美容应用相结合。一些特定于成年女性的因素会影响治疗的选择，包括老年皮肤更容易受到刺激、可能对治疗反应较慢、良好的依从性可能性较高、是否处于生育年龄，以及疾病对心理社会的影响。应通过进一步的患者教育和简化方案来鼓励患者坚持治疗，该方案应根据个体患者的需求和生活方式量身定制。本文综述了成年女性痤疮的特定特征，并为该患者群体的痤疮治疗提供了建议。
