Klevens R Monina, Moorman Anne C
Dr. Klevens is a medical epidemiologist, Division of Viral Hepatitis, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Mailstop G-37, 1600 Clifton Road, Atlanta, Ga. 30333,
J Am Dent Assoc. 2013 Dec;144(12):1340-7. doi: 10.14219/jada.archive.2013.0069.
and Overview. Changes in the science of hepatitis C virus (HCV) infection and transmission in a private dental practice provide an opportunity to update dental health care providers about this pathogen. The authors' aims in this review were to create awareness of health care- associated transmission of hepatitis C and provide an update on the changes in testing and treatment. The authors include data from population-based epidemiologic surveys, clinical practice guidelines, surveillance reports and practice protocols.
In the United States, the elevated prevalence of chronic HCV infection among baby boomers-people born during the period from 1945 through 1965-led the Centers for Disease Control and Prevention to release new national screening guidelines. The authors summarize information about the natural history and epidemiology of hepatitis C and describe the new guidelines and novel treatment options. In addition, the authors provide an overview of how outbreaks of health care-associated HCV are detected and prevented. Practical Implications. Because dental health care professionals likely will treat people with current infection, education in the current science of HCV infection is useful.
背景与概述。私人牙科诊所中丙型肝炎病毒（HCV）感染与传播科学方面的变化，为向牙科保健提供者介绍这种病原体提供了契机。作者撰写本综述的目的是提高对医疗保健相关丙型肝炎传播的认识，并提供检测与治疗方面变化的最新情况。作者纳入了基于人群的流行病学调查、临床实践指南、监测报告及实践方案中的数据。
在美国，婴儿潮一代（出生于1945年至1965年期间的人群）中慢性HCV感染患病率升高，促使疾病控制与预防中心发布了新的全国筛查指南。作者总结了丙型肝炎的自然史和流行病学信息，并描述了新指南及新的治疗选择。此外，作者还概述了如何检测和预防医疗保健相关HCV的暴发。实际意义。由于牙科保健专业人员可能会治疗当前感染的患者，因此开展关于当前HCV感染科学知识的教育很有必要。
