Brent David A, McMakin Dana L, Kennard Betsy D, Goldstein Tina R, Mayes Taryn L, Douaihy Antoine B
University of Pittsburgh and Western Psychiatric Institute and Clinic.
J Am Acad Child Adolesc Psychiatry. 2013 Dec;52(12):1260-71. doi: 10.1016/j.jaac.2013.09.009. Epub 2013 Sep 29.
To review the studies that test treatments targeting adolescent suicidal ideation, suicide attempts, or self-harm, and to make recommendations for future intervention development.
The extant randomized clinical trials that aim to reduce the intensity of suicidal ideation or the recurrence of suicide attempts or self-harm were reviewed with respect to treatment components, comparison treatments, sample composition, and outcomes.
The majority of studies that showed any effect on suicidal ideation, attempts, or self-harm had some focus on family interactions or nonfamilial sources of support. Two of the most efficacious interventions also provided the greatest number of sessions. Some other treatment elements associated with positive effects include addressing motivation for treatment and having explicit plans for integrating the experimental treatment with treatment as usual. In many studies, suicidal events tend to occur very early in the course of treatment prior to when an effective "dose" of treatment could be delivered. Important factors that might mitigate suicidal risk, such as sobriety, healthy sleep, and promotion of positive affect, were not addressed in most studies.
Interventions that can front-load treatment shortly after the suicidal crisis, for example, while adolescent suicide attempters are hospitalized, may avert early suicidal events. Treatments that focus on the augmentation of protective factors, such as parent support and positive affect, as well as the promotion of sobriety and healthy sleep, may be beneficial with regard to the prevention of recurrent suicidal ideation, attempts, or self-harm in adolescents.
回顾针对青少年自杀意念、自杀未遂或自我伤害的治疗测试研究,并为未来干预措施的发展提出建议。
对旨在降低自杀意念强度或自杀未遂或自我伤害复发率的现有随机临床试验,从治疗组成部分、对照治疗、样本构成和结果等方面进行了综述。
大多数对自杀意念、未遂或自我伤害有任何影响的研究都有一些聚焦于家庭互动或非家庭支持来源。两种最有效的干预措施也是疗程最多的。其他一些与积极效果相关的治疗要素包括解决治疗动机以及制定将实验性治疗与常规治疗相结合的明确计划。在许多研究中,自杀事件往往在治疗过程的早期就发生,此时还未给予有效的“治疗剂量”。大多数研究未涉及一些可能减轻自杀风险的重要因素,如清醒、健康睡眠和促进积极情绪。
能够在自杀危机后不久(例如,在青少年自杀未遂者住院期间)提前进行治疗的干预措施,可能避免早期自杀事件。专注于增强保护因素(如父母支持和积极情绪)以及促进清醒和健康睡眠的治疗方法,可能对预防青少年复发性自杀意念、未遂或自我伤害有益。