Jones Nicholas P
The Royal Eye Hospital , Manchester , UK.
Ocul Immunol Inflamm. 2015 Apr;23(2):118-26. doi: 10.3109/09273948.2013.855799. Epub 2013 Dec 2.
To demonstrate the demography, anatomical, and diagnostic classification of patients with uveitis attending the Manchester Uveitis Clinic (MUC), a specialist uveitis clinic in the northwest of England, UK.
Retrospective retrieval of data on a computerized database incorporating all new referrals to MUC from 1991 to 2013.
A total of 3000 new patients with uveitis were seen during a 22-year period. The anatomical types seen were anterior 46%; intermediate 11.1%; posterior 21.8%; and panuveitis 21.1%. The most common diagnoses were Fuchs heterochromic uveitis (11.5% of total), sarcoidosis-related uveitis (9.7%), idiopathic intermediate uveitis (7.9%), idiopathic acute anterior uveitis (7.0%), and toxoplasmosis (6.9%). Syphilis and tuberculosis-associated uveitis increased markedly in frequency during the study period.
The uveitis casemix in this region reflects a predominantly white Caucasian population in a temperate country, but with changing characteristics owing to increasing immigration, enhanced diagnostic techniques, changes in referral pattern, and some real changes in disease incidence.
展示英国曼彻斯特葡萄膜炎诊所（MUC）（位于英国西北部的一家专业葡萄膜炎诊所）葡萄膜炎患者的人口统计学、解剖学及诊断分类情况。
从1991年至2013年所有转诊至MUC的新患者数据的计算机化数据库中进行回顾性检索。
在22年期间共诊治了3000例葡萄膜炎新患者。所见的解剖学类型为：前部46%；中间部11.1%；后部21.8%；全葡萄膜炎21.1%。最常见的诊断为：富克斯异色性葡萄膜炎（占总数的11.5%）、结节病相关性葡萄膜炎（9.7%）、特发性中间葡萄膜炎（7.9%）、特发性急性前部葡萄膜炎（7.0%）和弓形虫病（6.9%）。在研究期间，梅毒和结核相关性葡萄膜炎的发病率显著增加。
该地区葡萄膜炎的病例组合反映了一个温带国家中以白种人为主的人群，但由于移民增加、诊断技术提高、转诊模式改变以及疾病发病率的一些实际变化，其特征也在发生改变。
