Abdelgaied Abdellatif, Brockett Claire L, Liu Feng, Jennings Louise M, Jin Zhongmin, Fisher John
Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK.
Proc Inst Mech Eng H. 2014 Jan;228(1):98-106. doi: 10.1177/0954411913513251. Epub 2013 Dec 2.
The mean average life is increasing; therefore, there is a need to increase the lifetime of the prostheses. To fulfil this requirement, new prosthetic designs and materials are being introduced. Two of the design parameters that may affect wear of total knee replacements, and hence the expected lifetime, are the insert conformity and material. Computational models have been used extensively for wear prediction and optimisation of artificial knee designs. The objective of the present study was to use a previously validated non-dimensional wear coefficient-based computational wear model to investigate the effect of insert conformity and material on the predicted wear in total knee replacements. Four different inserts (curved, lipped, partial flat and custom flat), with different conformity levels, were tested against the same femoral and under two different kinematic inputs (intermediate and high), with different levels of cross-shear. The insert bearing materials were either conventional or moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE). Wear predictions were validated against the experimental data from Leeds knee simulation tests. The predicted wear rates for the curved insert (most conformed) were more than three times those for the flat insert (least conformed). In addition, the computationally predicted average volumetric wear rates for moderately cross-linked UHMWPE bearings were less than half of their corresponding conventional UHMWPE bearings. Moreover, the wear of the moderately cross-linked UHMWPE was shown to be less dependent on the degree of cross-shear, compared to conventional UHMWPE. These results along with supporting experimental studies provide insight into the design variables, which may reduce wear in knee replacements.
平均寿命在增加;因此,有必要延长假体的使用寿命。为满足这一要求,正在引入新的假体设计和材料。可能影响全膝关节置换磨损,进而影响预期使用寿命的两个设计参数是衬垫贴合度和材料。计算模型已被广泛用于人工膝关节设计的磨损预测和优化。本研究的目的是使用先前验证的基于无量纲磨损系数的计算磨损模型,来研究衬垫贴合度和材料对全膝关节置换预测磨损的影响。针对四种不同的衬垫(弧形、带唇缘、部分平面和定制平面),它们具有不同的贴合度水平,在相同的股骨部件上进行测试,并在两种不同的运动输入(中等和高)下进行测试,这两种运动输入具有不同程度的交叉剪切。衬垫的承载材料要么是传统的超高分子量聚乙烯(UHMWPE),要么是适度交联的超高分子量聚乙烯。磨损预测结果与利兹膝关节模拟试验的实验数据进行了验证。弧形衬垫(贴合度最高)的预测磨损率是平面衬垫(贴合度最低)的三倍多。此外,计算预测的适度交联超高分子量聚乙烯轴承的平均体积磨损率不到相应传统超高分子量聚乙烯轴承的一半。而且,与传统超高分子量聚乙烯相比,适度交联超高分子量聚乙烯的磨损对交叉剪切程度的依赖性较小。这些结果以及相关的实验研究为可能减少膝关节置换磨损的设计变量提供了见解。