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2010年1月至2011年8月中国上海的急性中毒类型及发生率

Acute poisoning types and prevalence in Shanghai, China, from January 2010 to August 2011.

作者信息

Zhang Jingshuo, Xiang Ping, Zhuo Xianyi, Shen Min

机构信息

Soochow University, Suzhou 215123, China; Department of Forensic Toxicology, Institute of Forensic Sciences, Ministry of Justice, Shanghai Key Laboratory of Forensic Medicine, Guangfu Xi Road 1347, Shanghai 200063, China.

出版信息

J Forensic Sci. 2014 Mar;59(2):441-6. doi: 10.1111/1556-4029.12334. Epub 2013 Dec 6.

Abstract

In recent years, the number of cases of acute poisoning has increased in China, yet; currently, there is no detailed report published that addresses acute poisoning in the mainland of China. We collected biological samples from 466 cases of suspected acute poisoning at the hospitals in Shanghai, China, and examined them using spectroscopy, chromatography and chromatography/mass spectrometry. Of the 466 cases, 230 cases (100 men and 130 women) were positively confirmed as acute poisonings. There were 80 types of compounds identified in this study. Medications were the most frequent substances identified, and the other substances included pesticides, multiple compounds, volatile compounds, natural toxins, and others. The results of this study indicate a need for strengthening the education about and management of the rational and safe use of drugs in Shanghai.

摘要

近年来,中国急性中毒病例数量有所增加,然而,目前尚无关于中国大陆急性中毒情况的详细报告发表。我们在中国上海的医院收集了466例疑似急性中毒病例的生物样本,并使用光谱法、色谱法和色谱/质谱法对其进行检测。在这466例病例中,有230例(100名男性和130名女性)被确诊为急性中毒。本研究共鉴定出80种化合物。药物是鉴定出的最常见物质,其他物质包括农药、多种化合物、挥发性化合物、天然毒素等。本研究结果表明,上海需要加强关于合理安全用药的教育和管理。

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