Berry S J, Strandberg J D, Saunders W J, Coffey D S
Prostate. 1986;9(4):363-73. doi: 10.1002/pros.2990090406.
The prevalence and growth of benign prostatic hyperplasia (BPH) in beagles as a function of age were studied. The normal prostate gland was 12 +/- 3 gm in beagles 2.1-3.0 years of age; this weight remained unchanged unless BPH developed. Histologic evidence of BPH developed at an early age with a prevalence of 16% of the dogs by the age 2 years. Fifty percent of the dogs had BPH, determined histopathologically by age 4.1-5.0 years. The average weight of the prostate gland remained constant until after age 8 years. With age, the pathologic features of BPH changed from glandular to the complex form, with no increase in prostate weight until after 8 years. Reinitiation of growth occurred and prostate weight increased to greater than 36 gm in eight of 185 beagles older than age 8 years.
研究了比格犬良性前列腺增生（BPH）的患病率及随年龄增长的情况。2.1至3.0岁比格犬的正常前列腺重量为12±3克；除非发生BPH，该重量保持不变。BPH的组织学证据在早期出现，2岁时患病率为16%。到4.1至5.0岁时，通过组织病理学确定50%的犬患有BPH。前列腺的平均重量在8岁之前保持恒定。随着年龄增长，BPH的病理特征从腺性转变为复杂形式，8岁后前列腺重量才增加。185只8岁以上的比格犬中有8只出现了再次生长，前列腺重量增加到超过36克。
