Allon Irit, Kaplan Ilana, Gal Gavriel, Chaushu Gavriel, Allon Dror M
Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Tel Aviv, 69978, Israel,
Med Oral Patol Oral Cir Bucal. 2014 Sep 1;19(5):e438-43. doi: 10.4317/medoral.19387.
To investigate the clinical characteristics and pre- biopsy provisional diagnoses of benign oral mucosal tumors.
A 10- year retrospective analysis of all benign tumors of the oral mucosa, from a university- affiliated oral and maxillofacial surgery department.
146 benign tumors were included. The mean age was 49.6 years, with an approximately equal gender distribution. The most prevalent tumor types were lipomatous tumors (27.4%), vascular (23.3%), and salivary gland tumors (16.5%). Tongue, labial and buccal mucosa were the most frequently involved sites. The vast majority (98.6%) presented as non-ulcerated masses. Only 2 (1.4%) presented as ulcerated masses. The clinical provisional diagnosis correctly classified lesions as non-malignant in 93.3%. In only 9 (6.7%) suspicion of malignancy was included in the provisional diagnosis. However, benignneoplasia was unsuspected in 42.1% of tumors. These cases were clinically classified as reactive.
Benign tumors were most likely to be clinically correctly classified as non-malignant, but even in the setting of experienced oral surgeons, neoplasia was unsuspected in more than 40% of cases. This data strongly supports the need to biopsy every oral mucosal mass, since inaccurate clinical evaluation of the lesion's biological nature was a frequent event.
研究口腔黏膜良性肿瘤的临床特征及活检前初步诊断情况。
对一所大学附属口腔颌面外科的所有口腔黏膜良性肿瘤进行为期10年的回顾性分析。
共纳入146例良性肿瘤。平均年龄为49.6岁，性别分布大致相等。最常见的肿瘤类型为脂肪瘤（27.4%）、血管性肿瘤（23.3%）和涎腺肿瘤（16.5%）。舌、唇和颊黏膜是最常受累的部位。绝大多数（98.6%）表现为非溃疡性肿块。仅2例（1.4%）表现为溃疡性肿块。临床初步诊断将病变正确分类为非恶性的比例为93.3%。初步诊断中仅9例（6.7%）怀疑为恶性。然而，42.1%的肿瘤未被怀疑为良性肿瘤。这些病例在临床上被分类为反应性病变。
良性肿瘤在临床上最有可能被正确分类为非恶性，但即使在经验丰富的口腔外科医生的情况下，超过40%的病例仍未被怀疑为肿瘤。这些数据有力地支持了对每个口腔黏膜肿块进行活检的必要性，因为对病变生物学性质的临床评估不准确是常有的事。
