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小鼠比目鱼肌钠钾泵活性:与体外及体内氧消耗直接相关。

Mouse soleus muscle Na-K pump activity: direct correlation with in vitro and in vivo oxygen consumption.

作者信息

Saddlier S, De Luise M

出版信息

Horm Metab Res. 1986 Nov;18(11):757-60. doi: 10.1055/s-2007-1012428.

DOI:10.1055/s-2007-1012428
PMID:2431989
Abstract

To evaluate the contribution of active sodium-potassium transport to energy utilization, measurements of sodium-potassium pump activity in isolated soleus muscles of normal mice were carried out and related to measurements of oxygen consumption by the tissue. A highly significant positive correlation (r = 0.89, p less than 0.001) was found between these two parameters. In addition, both the in vitro oxygen consumption and Na-K pump activity of the muscles were found to correlate with whole body oxygen utilization by the experimental animals. The results support a role for the sodium-potassium pump in the determination of energy turnover.

摘要

为评估钠钾主动转运对能量利用的贡献,对正常小鼠分离的比目鱼肌中的钠钾泵活性进行了测量,并将其与组织耗氧量的测量结果相关联。发现这两个参数之间存在高度显著的正相关(r = 0.89,p小于0.001)。此外,还发现肌肉的体外耗氧量和钠钾泵活性均与实验动物的全身氧利用相关。这些结果支持钠钾泵在能量周转测定中发挥作用。

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