Gillespie N C, Lewis R J, Pearn J H, Bourke A T, Holmes M J, Bourke J B, Shields W J
Med J Aust. 1986;145(11-12):584-90.
Ciguatera is a type of food poisoning that results from eating certain tropical fish which have become toxic. It is common in Australia: 175 outbreaks, which involved 527 people, were reported in Queensland between 1965 and 1984. It seems restricted to certain areas around the Australian coastline. Most reports have involved the narrow-barred Spanish mackerel, Scomberomorus commersoni, most of which were caught in southern Queensland waters. Up to 2100 cases may have occurred in north Queensland between 1965 and 1984, which were not recorded by the writers. The symptoms of ciguatera in Australia are similar to those reported elsewhere in the South Pacific. Ciguatoxin acts by increasing the permeability of excitable membranes to sodium ions. This type of membrane is found throughout the body in nerve tissue as well as in heart and skeletal muscle. The treatment of ciguatera remains symptomatic and supportive only. Major advances in treatment for ciguatera and detection of ciguatoxin await the means of producing additional ciguatoxin.
雪卡毒素中毒是一种食物中毒，由食用某些已产生毒素的热带鱼类引起。在澳大利亚很常见：1965年至1984年间，昆士兰州报告了175起疫情，涉及527人。它似乎局限于澳大利亚海岸线周围的某些地区。大多数报告都涉及窄体西班牙鲭，即康氏马鲛，其中大部分是在昆士兰州南部水域捕获的。1965年至1984年间，北昆士兰可能发生了多达2100例病例，但作者并未记录。澳大利亚雪卡毒素中毒的症状与南太平洋其他地方报告的症状相似。雪卡毒素通过增加可兴奋膜对钠离子的通透性起作用。这种类型的膜在全身的神经组织以及心脏和骨骼肌中都有发现。雪卡毒素中毒的治疗仍然只是对症和支持性的。雪卡毒素中毒治疗和雪卡毒素检测的重大进展有待于生产更多雪卡毒素的方法。
