Haig A J, Katz R T, Sahgal V
Arch Phys Med Rehabil. 1987 Jan;68(1):24-7.
The locked-in syndrome is a severe disability consisting of quadriplegia and anarthria with preserved consciousness. No large series of cases have been reported and very few cases of long-term survival have been described. We present a follow-up of 27 patients "locked-in" for more than one year. Twenty-four were still alive up to 12.5 years after onset, with a mean survival of 4.9 years. Significant recovery was noted in only a few patients. Seventeen patients lived at home at the time of study. Eight were never hospitalized after the initial event. Gastrostomy and tracheostomy tubes and indwelling catheters were eventually removed from many patients. Electronic devices were used by ten patients to facilitate communication. We conclude that rehabilitation and medical care must be planned carefully, given the length of survival shown in this group.
闭锁综合征是一种严重的残疾状态，表现为四肢瘫痪和构音障碍，但意识保留。目前尚无大量病例系列报道，且很少有长期存活病例的描述。我们对27例“闭锁”状态超过一年的患者进行了随访。其中24例在发病后长达12.5年仍存活，平均存活时间为4.9年。仅少数患者有明显恢复。在研究时，17例患者在家中生活。8例在初始事件后从未住院。许多患者最终拔除了胃造瘘管、气管造口管和留置导管。10例患者使用电子设备辅助交流。鉴于该组患者所显示的存活时长，我们得出结论，必须仔细规划康复和医疗护理。
