Gamble J, Jones W, Minshall S
Environ Res. 1987 Feb;42(1):201-14. doi: 10.1016/s0013-9351(87)80022-1.
Personal samples of nitrogen dioxide (NO2) and respirable particulate (RP) were collected over the shift on 232 workers in four diesel bus garages. Response was assessed by an acute respiratory questionnaire and before and after shift spirometry. Measures of exposure to NO2 and RP were associated with work-related symptoms of cough; itching, burning, or watering eyes; difficult or labored breathing; chest tightness; and wheeze. The prevalence of burning eyes, headaches, difficult or labored breathing, nausea, and wheeze experienced at work were higher in the diesel bus garage workers than in a comparison population of battery workers, while the prevalence of headaches was reduced. Mean reductions in forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), peak flow, and flows at 50 and 75% of FVC were not obviously different from zero. There was no detectable association of exposure to NO2 or respirable particulate and acute reductions in pulmonary function. Workers who often had respiratory work-related symptoms generally had a slightly greater mean acute reduction in FEV1 and FEF50 than did those who did not have these symptoms, but these differences were not statistically significant.
在四个柴油公交停车场对232名工人在轮班期间采集了二氧化氮（NO₂）和可吸入颗粒物（RP）的个人样本。通过急性呼吸道问卷以及轮班前和轮班后的肺活量测定来评估反应。二氧化氮和可吸入颗粒物的接触量与咳嗽、眼睛瘙痒、灼痛或流泪、呼吸困难或费力、胸闷和喘息等与工作相关的症状有关。柴油公交停车场工人在工作时出现眼睛灼痛、头痛、呼吸困难或费力、恶心和喘息的患病率高于电池工人对照组，而头痛患病率有所降低。用力肺活量（FVC）、第1秒用力呼气量（FEV₁）、峰值流量以及FVC的50%和75%时的流量的平均降低值与零无明显差异。未检测到二氧化氮或可吸入颗粒物暴露与肺功能急性降低之间存在关联。经常出现与呼吸相关工作症状的工人，其FEV₁和FEF50的平均急性降低值通常比没有这些症状的工人略大，但这些差异无统计学意义。
