King Charles H
Center for Global Health and Diseases, Case Western Reserve University School of Medicine, 2109 Adelbert Road, BRB Room 422, Cleveland, OH 44106, USA.
Acta Trop. 2015 Jan;141(Pt B):150-60. doi: 10.1016/j.actatropica.2013.12.001. Epub 2013 Dec 12.
Health metrics based on health-adjusted life years have become standard units for comparing the disease burden and treatment benefits of individual health conditions. The Disability-Adjusted Life Year (DALY) and the Quality-Adjusted Life Year (QALY) are the most frequently used in cost-effect analyses in national and global health policy discussions for allocation of health care resources. While sometimes useful, both the DALY and QALY metrics have limitations in their ability to capture the full health impact of helminth infections and other 'neglected tropical diseases' (NTDs). Gaps in current knowledge of disease burden are identified, and interim approaches to disease burden assessment are discussed.
基于健康调整生命年的健康指标已成为比较个体健康状况的疾病负担和治疗效益的标准单位。伤残调整生命年（DALY）和质量调整生命年（QALY）是国家和全球卫生政策讨论中用于卫生保健资源分配的成本效益分析中最常用的指标。虽然有时有用，但DALY和QALY指标在全面反映蠕虫感染和其他“被忽视的热带病”（NTDs）对健康的影响方面都存在局限性。本文指出了当前疾病负担知识方面的差距，并讨论了疾病负担评估的临时方法。
