Engelsma Marc Y, Way Keith, Dodge Melanie J, Voorbergen-Laarman Michal, Panzarin Valentina, Abbadi Miriam, El-Matbouli Mansour, Frank Skall Helle, Kahns Søren, Stone David M
Central Veterinary Institute (CVI), part of Wageningen UR, PO Box 65, 8200 AB Lelystad, The Netherlands.
Dis Aquat Organ. 2013 Dec 12;107(2):113-20. doi: 10.3354/dao02666.
Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.
鲤疱疹病毒3型（CyHV - 3）或锦鲤疱疹病毒（KHV）是一种对鲤鱼具有毁灭性的病毒。使用针对鲤疱疹病毒DNA聚合酶和主要衣壳蛋白基因的通用引物，获得了与先前描述的CyHV - 3不同的核苷酸序列。至少鉴定出3组假定的类CyHV - 3病毒，它们与CyHV - 3毒株的核苷酸同一性为95%至98%。携带CyHV - 3变体的鲤鱼未表现出与CyHV - 3感染一致的临床症状，且其来源地没有实际的CyHV - 3疫情爆发。这些毒株可能代表CyHV - 3的低致病性或无致病性变体。
