Barnoiu Ovidiu-Spiru, Garcia Galisteo Emilio, Baron Lopez Francisco, Vozmediano Chicharro Raul, Soler Martinez Jorge, Del Rosal Samaniego Jose Maria, Machuca Santacruz Javier, Baena Gonzalez Victor
Department of Urology, Carlos Haya Hospital, Malaga, Spain.
Urol Int. 2014;92(3):306-9. doi: 10.1159/000354352. Epub 2013 Dec 5.
To assess the preoperative urodynamic predictors of urinary incontinence (UI) 1 year after robot-assisted radical prostatectomy (RARP) and to design a nomogram capable of predicting its occurrence.
Our prospective study included 58 previously continent patients who underwent RARP, in most cases, bilateral nerve-sparing and bladder neck preservation. A urodynamic examination including a urethral pressure profile was performed preoperatively. Multivariate analysis was used to assess the predictors for the need to use 1 or more pads/day and a nomogram was constructed.
There was a 20.6% incidence of UI at 1 year after RARP. Bladder compliance, maximum urethral closure pressure and the development of bladder outlet obstruction, correlated well with the incidence of UI on the multivariate analysis (p = 0.043, 0.001, and 0.05, respectively).
Bladder compliance <27.8 ml/cm H2O, maximum urethral closure pressure <50.3 cm H2O and the bladder outlet obstruction are independent urodynamic factors correlating with UI after RARP. The new nomogram can objectively predict a patient likelihood of requiring 1 or more pads/day 1 year after RARP with a good accuracy.
评估机器人辅助根治性前列腺切除术(RARP)术后1年尿失禁(UI)的术前尿动力学预测指标,并设计一种能够预测其发生的列线图。
我们的前瞻性研究纳入了58例既往控尿的患者,这些患者接受了RARP,大多数情况下进行了双侧神经保留和膀胱颈保留。术前进行了包括尿道压力分布的尿动力学检查。采用多变量分析评估每天需要使用1个或更多尿垫的预测因素,并构建列线图。
RARP术后1年UI的发生率为20.6%。在多变量分析中,膀胱顺应性、最大尿道闭合压和膀胱出口梗阻的发生与UI的发生率密切相关(分别为p = 0.043、0.001和0.05)。
膀胱顺应性<27.8 ml/cm H2O、最大尿道闭合压<50.3 cm H2O和膀胱出口梗阻是与RARP术后UI相关的独立尿动力学因素。新的列线图能够客观地预测患者在RARP术后1年每天需要使用1个或更多尿垫的可能性,准确性良好。