Zhang Wei-lan, Li Min, Zhang Bo, Geng Hai-yang, Liang Yin-qiang, Xu Ke, Li Song-bai
Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang City, China.
PLoS One. 2013 Dec 5;8(12):e81486. doi: 10.1371/journal.pone.0081486. eCollection 2013.
We aimed to assess the effectiveness and feasibility of head-and-neck Computed Tomography Angiography (CTA) with low tube voltage and low concentration contrast media combined with iterative reconstruction algorithm.
92 patients were randomly divided into group A and B: patients in group A received a conventional scan with 120 kVp and contrast media of 320 mgI/ml. Patients in group B, 80 kVp and contrast media of 270 mgI/ml were used along with iterative reconstruction algorithm techniques. Image quality, radiation dose and the effectively consumed iodine amount between two groups were analyzed and compared.
Image quality of CTA of head-and-neck vessels obtained from patients in group B was significantly improved quantitatively and qualitatively. In addition, CT attenuation values in group B were also significantly higher than that in group A (p<0.001). Furthermore, compared with the protocol whereby 120 kVp and 320 mgI/dl were administrated, the mean radiation dose and consumed iodine amount in protocol B were also reduced by 50% and 15.6%, respectively (p<0.001).
With the help of iterative reconstruction algorithm techniques, the head-and-neck CTA with diagnostic quality can be adequately acquired with low tube voltage and low concentration contrast media. This method could be potentially extended to include any part of the body to reduce the risks related to ionizing radiation.
我们旨在评估低管电压、低浓度造影剂联合迭代重建算法的头颈部计算机断层血管造影(CTA)的有效性和可行性。
92例患者随机分为A组和B组:A组患者接受120 kVp的常规扫描及320 mgI/ml的造影剂。B组患者使用80 kVp及270 mgI/ml的造影剂,并采用迭代重建算法技术。分析并比较两组之间的图像质量、辐射剂量及有效碘摄入量。
B组患者获得的头颈部血管CTA图像质量在定量和定性方面均有显著改善。此外,B组的CT衰减值也显著高于A组(p<0.001)。此外,与采用120 kVp和320 mgI/dl的方案相比,方案B的平均辐射剂量和碘摄入量也分别降低了50%和15.6%(p<0.001)。
借助迭代重建算法技术,使用低管电压和低浓度造影剂即可充分获得具有诊断质量的头颈部CTA。该方法可能会推广至身体的任何部位,以降低与电离辐射相关的风险。