Dissemond J
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Deutschland,
Hautarzt. 2014 Jan;65(1):10-4. doi: 10.1007/s00105-013-2635-9.
The importance of bacteria in the treatment of patients with chronic wounds has been a focus of attention in recent years. A bacteriological swab taken from the wound in a Essen rotary technique is usually adequate for the diagnosis. The current detection rate of bacteria in patients with chronic leg ulcers in Germany is about 50 % for Staphylococcus aureus, 30 % for Pseudomonas aeruginosa and Enterobacteriaceae and approximately 10 % for MRSA. Most of these patients have a clinically unimportant bacterial colonization, so that systemic administration of antibiotics usually is not required. For wound cleansing only sterile solutions such as Ringer's or physiological saline solution should be used. If tap water is used, then the use of sterile filters is strongly recommended. In patients with increased risk of infection, a critical colonization or local signs of infection, modern wound antiseptics using polyhexanide or octenidine are available. The use of systemic antibiotics should be strictly limited to patients with systemic signs of infections.
近年来,细菌在慢性伤口患者治疗中的重要性一直是人们关注的焦点。采用埃森旋转技术从伤口采集的细菌学拭子通常足以用于诊断。目前德国慢性腿部溃疡患者中金黄色葡萄球菌的细菌检出率约为50%,铜绿假单胞菌和肠杆菌科为30%,耐甲氧西林金黄色葡萄球菌约为10%。这些患者中的大多数存在临床上无重要意义的细菌定植,因此通常不需要全身性使用抗生素。伤口清洁仅应使用无菌溶液,如林格氏液或生理盐水溶液。如果使用自来水,强烈建议使用无菌过滤器。对于感染风险增加、存在严重定植或局部感染迹象的患者,可使用含聚己双胍或奥替尼啶的现代伤口消毒剂。全身性抗生素的使用应严格限于有全身感染迹象的患者。