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为扩大非洲轮状病毒疫苗的使用规模做准备:建立监测平台以监测疾病负担和疫苗效果。

Preparing for the scale-up of rotavirus vaccine introduction in Africa: establishing surveillance platforms to monitor disease burden and vaccine impact.

机构信息

From the *World Health Organization, Regional Office for Africa, Brazzaville, Republic of Congo, †National Center for Immunization and Respiratory Diseases, CDC, Atlanta, Georgia; and ‡Bill & Melinda Gates Foundation, Seattle, Washington.

出版信息

Pediatr Infect Dis J. 2014 Jan;33 Suppl 1(Suppl 1):S1-5. doi: 10.1097/INF.0000000000000132.

DOI:10.1097/INF.0000000000000132
PMID:24343605
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11977321/
Abstract

Countries in Africa have begun introducing rotavirus vaccines in their national immunization programs, and wide-scale rollout across the continent is expected during the next few years. In preparation for vaccine introduction, many countries initiated surveillance for rotavirus and other studies to document disease burden, to describe the epidemiology and to monitor circulating rotavirus strains in Africa. In addition, 2 countries sought to systematically investigate cases of intussusception, a rare adverse event that has been associated with rotavirus vaccines in some settings. The ongoing surveillance provided data that will serve as a baseline against which the impact of rotavirus vaccines in Africa can be assessed.

摘要

非洲国家已开始在国家免疫规划中引入轮状病毒疫苗,预计未来几年将在整个非洲大陆大规模推广。为了准备疫苗的引入,许多国家启动了轮状病毒和其他研究的监测,以记录疾病负担,描述流行病学,并监测非洲流行的轮状病毒株。此外,有 2 个国家试图系统地调查肠套叠病例,肠套叠是一种罕见的不良事件,在某些情况下与轮状病毒疫苗有关。正在进行的监测提供了数据,将作为评估轮状病毒疫苗在非洲的影响的基线。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42c/11977321/b811f51664f3/nihms-2071840-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42c/11977321/3ebb8bc297e8/nihms-2071840-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42c/11977321/b811f51664f3/nihms-2071840-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42c/11977321/3ebb8bc297e8/nihms-2071840-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42c/11977321/b811f51664f3/nihms-2071840-f0002.jpg

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Can routinely collected national data on childhood morbidity and mortality from diarrhea be used to monitor health impact of rotavirus vaccination in Africa? Examination of pre-vaccine baseline data from Rwanda.能否利用常规收集的国家儿童腹泻发病率和死亡率数据监测轮状病毒疫苗接种对非洲的健康影响?对卢旺达疫苗接种前基线数据的考察。
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