Virani Aneesha, Kunduk Melda, Fink Daniel S, McWhorter Andrew J
Department of Communication Sciences and Disorders, Louisiana State University, Baton Rouge, Louisiana.
Head Neck. 2015 Feb;37(2):162-70. doi: 10.1002/hed.23570. Epub 2014 Mar 17.
This study investigated the effects of 2 different swallowing exercise regimens performed during radiation therapy with/without chemotherapy on swallowing function.
Fifty patients were recruited prospectively to 2 groups (the exercise group, n = 26 and the repetitive swallow group, n = 24). Functional Oral Intake Scale (FOIS) scores and percutaneous endoscopic gastrostomy (PEG) placements were compared at posttreatment and at 3 months.
The exercise group eliminated significantly more PEG tubes at 3 months posttreatment compared to the swallow group (16% vs 50%). Among patients who received both radiation and chemotherapy, the exercise group had significantly less PEG tubes immediately posttreatment as well as 3 months posttreatment (35% and 10%), compared to the swallow group (69% and 50%).
Findings indicate significant benefits of the exercise group's exercise regimen in reducing PEG dependence and oral intake difficulties.
本研究调查了在放疗期间进行的两种不同吞咽锻炼方案（联合或不联合化疗）对吞咽功能的影响。
前瞻性招募50名患者分为两组（锻炼组，n = 26；重复吞咽组，n = 24）。比较治疗后及3个月时的功能性经口进食量表（FOIS）评分和经皮内镜下胃造口术（PEG）置管情况。
与吞咽组相比，锻炼组在治疗后3个月拔除的PEG管显著更多（16% 对50%）。在接受放疗和化疗的患者中，与吞咽组（69%和50%）相比，锻炼组在治疗后即刻及治疗后3个月时的PEG管显著更少（35%和10%）。
研究结果表明锻炼组的锻炼方案在降低PEG依赖和经口进食困难方面有显著益处。
