Prakash S Krishna
Department of Microbiology, Maulana Azad Medical College, New Delhi, India.
Dent Res J (Isfahan). 2013 Sep;10(5):585-91.
Dental abscess is a frequently occurring infectious process known to the health practice. The fate of the infection depends on the virulence of the bacteria, host resistance factors, and regional anatomy. Serious consequences arising from the spread of a dental abscess lead to significant morbidity and mortality. Acute dental abscess is polymicrobial, comprising of strict anaerobes, such as anaerobic cocci, Prevotella, Fusobacterium species, and facultative anaerobes, such as viridans group streptococci and the Streptococcus anginosus group. Numerous novel, uncultivable and fastidious organisms have been identified as potential pathogens with the use of non-culture techniques. The majority of localized dental abscesses respond to surgical treatment while the use of antimicrobials is limited to severe spreading infections. There is a need for good-quality clinical trials of sufficient size to identify the ideal treatment. The microbiology of the acute dentoalveolar abscess and its treatment in the light of improved culture and diagnostic methods are reviewed.
牙脓肿是医疗实践中常见的感染性疾病。感染的转归取决于细菌的毒力、宿主抵抗因素和局部解剖结构。牙脓肿扩散引起的严重后果会导致显著的发病率和死亡率。急性牙脓肿是多微生物感染,包括严格厌氧菌,如厌氧球菌、普雷沃菌属、梭杆菌属,以及兼性厌氧菌,如草绿色链球菌群和咽峡炎链球菌群。利用非培养技术已鉴定出许多新的、不可培养的和苛求性微生物为潜在病原体。大多数局限性牙脓肿对手术治疗有反应,而抗菌药物的使用仅限于严重的播散性感染。需要有足够规模的高质量临床试验来确定理想的治疗方法。本文综述了急性牙槽脓肿的微生物学及其在改进培养和诊断方法后的治疗。