Holls W M, Thomas J, Troyer V
Obstet Gynecol. 1987 Mar;69(3 Pt 1):354-7.
The group B beta-hemolytic streptococcus has been implicated in significant maternal and neonatal infections. The usual criteria for identifying the organism has been culture. A preliminary prospective study of the applicability of a simple, rapid, and readily available inexpensive screening tool, the Gram stain, was evaluated in 98 high-risk patients (premature rupture of the membranes and/or premature labor). In this selected population, cervical Gram stain was found to have a 98% negative predictive value for subsequent culture-proven group B beta-hemolytic streptococcus colonization. The sensitivity, specificity, and positive predictive values were, respectively, 93, 69, and 33%. Gram stain may be an appropriate test to assist in evaluation of group B beta-hemolytic streptococcus colonization in an at-risk population.
B族β溶血性链球菌与严重的孕产妇和新生儿感染有关。鉴定该病原体的常用标准是培养。对一种简单、快速且易于获得的廉价筛查工具——革兰氏染色法的适用性进行了一项初步前瞻性研究，该研究在98例高危患者（胎膜早破和/或早产）中进行评估。在这个特定人群中，发现宫颈革兰氏染色对随后经培养证实的B族β溶血性链球菌定植具有98%的阴性预测值。其敏感性、特异性和阳性预测值分别为93%、69%和33%。革兰氏染色可能是一种合适的检测方法，有助于评估高危人群中的B族β溶血性链球菌定植情况。
