Zhang Ping, Li Fengjuan, Liang Weili, Li Jie, Kan Biao, Wang Duochun
National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention/State Key Laboratory for Infectious Disease Prevention and Control, Beijing, and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
J Clin Microbiol. 2014 Mar;52(3):964-7. doi: 10.1128/JCM.03121-13. Epub 2013 Dec 18.
A total of 330 clinical Vibrio cholerae O1 serogroups from China dating between 1961 and 2010 were investigated. By phenotypic biotyping and genetic analysis, during the seventh pandemic of V. cholerae O1 in China, the isolates of hybrid biotype (mixed classical phenotypes) were present during the entire1961-2010 period, while El Tor genetic shifts appeared in 1992 and replaced the prototype El Tor from 2002 to 2010.
对1961年至2010年间来自中国的总共330株霍乱弧菌O1血清群进行了调查。通过表型生物分型和基因分析发现,在中国霍乱弧菌O1第七次大流行期间,杂交生物型(混合经典表型)的分离株在1961 - 2010年整个期间均有出现,而埃尔托生物型的基因转变出现在1992年,并在2002年至2010年取代了原始埃尔托生物型。