School of Psychology, The University of Adelaide.
Neuropsychology. 2014 May;28(3):394-405. doi: 10.1037/neu0000025. Epub 2013 Dec 23.
The purpose of this study was to examine the relationship between subjective and objective assessments of memory and attention in people with chronic fatigue syndrome (CFS), using tests that have previously detected deficits in CFS samples and measures of potential confounds.
Fifty people with CFS and 50 healthy controls were compared on subjective (memory and attention symptom severity, Cognitive Failures Questionnaire, Everyday Attention Questionnaires) and objective (California Verbal Learning Test, Rey-Osterreith Complex Figure Test, Paced Auditory Serial Addition Test, Stroop task) measures of memory and attention. Fatigue, sleep, depression, and anxiety were also assessed.
The CFS group reported experiencing more cognitive problems than the controls, but the two groups did not differ on the cognitive tests. Scores on the subjective and objective measures were not correlated in either group. Depression was positively correlated with increased severity of cognitive problems in both the CFS and control groups.
There is little evidence for a relationship between subjective and objective measures of cognitive functioning for both people with CFS and healthy controls, which suggests that they may be capturing different constructs. Problems with memory and attention in everyday life are a significant part of CFS. Depression appears to be related to subjective problems but does not fully explain them.
本研究旨在通过对先前检测到慢性疲劳综合征（CFS）样本缺陷的测试和潜在混杂因素的测量，来检验 CFS 患者主观和客观的记忆和注意力评估之间的关系。
将 50 名 CFS 患者和 50 名健康对照者在记忆和注意力的主观（记忆和注意力症状严重程度、认知失误问卷、日常注意力问卷）和客观（加利福尼亚语言学习测试、 Rey-Osterreith 复杂图形测试、Paced Auditory Serial Addition Test、Stroop 任务）测试上进行了比较。同时还评估了疲劳、睡眠、抑郁和焦虑。
CFS 组报告的认知问题比对照组多，但两组在认知测试上没有差异。两组的主观和客观测量评分均不相关。在 CFS 组和对照组中，抑郁与认知问题严重程度的增加呈正相关。
对于 CFS 患者和健康对照组，主观和客观认知功能测量之间几乎没有关系的证据，这表明它们可能反映了不同的结构。日常生活中记忆和注意力的问题是 CFS 的一个重要组成部分。抑郁似乎与主观问题有关，但并不能完全解释这些问题。
