Dubey Suchita, Maity Siddhartha, Singh Mahendra, Saraf Shubhini A, Saha Sudipta
Department of Pharmaceutical Sciences, School of Bioscience and Biotechnology, Babasaheb Bhimrao Ambedkar University, Lucknow, Uttar Pradesh 226025, India.
Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal 700032, India.
Adv Pharmacol Sci. 2013;2013:423750. doi: 10.1155/2013/423750. Epub 2013 Nov 26.
Spilanthes acmella is an important medicinal plant, found in tropical and subtropical countries mainly India and South America. Popularly, it is known as toothache plant which reduces the pain associated with toothaches and can induce saliva secretion. Various extracts and active metabolites from various parts of this plant possess useful pharmacological activities. Literature survey proposed that it has multiple pharmacological actions, which include antifungal, antipyretic, local anaesthetic, bioinsecticide, anticonvulsant, antioxidant, aphrodisiac, analgesic, pancreatic lipase inhibitor, antimicrobial, antinociception, diuretic, vasorelaxant, anti-human immunodeficiency virus, toothache relieve and anti-inflammatory effects. This review is elaborately describing the traditional uses, phytochemistry, pharmacology, and toxicology of this plant. This review would assist researchers to search scientific information in the future.
金纽扣是一种重要的药用植物，主要分布在热带和亚热带国家，如印度和南美洲。通常，它被称为牙痛草，能减轻与牙痛相关的疼痛并能促进唾液分泌。该植物各部位的各种提取物和活性代谢物具有有益的药理活性。文献调查表明它具有多种药理作用，包括抗真菌、解热、局部麻醉、生物杀虫剂、抗惊厥、抗氧化、壮阳、止痛、胰腺脂肪酶抑制、抗菌、抗伤害感受、利尿、血管舒张、抗人类免疫缺陷病毒、缓解牙痛和抗炎作用。本综述详细描述了这种植物的传统用途、植物化学、药理学和毒理学。本综述将有助于研究人员在未来查找科学信息。
