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SuperUlam 对注意力和情绪的支持作用:一项随机、双盲、安慰剂对照交叉研究。

Effects of SuperUlam on Supporting Concentration and Mood: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

机构信息

Medicus Research, LLC, 18250 Roscoe Boulevard, Suite 240, Northridge, CA 91325, USA ; Northridge Hospital Integrative Medicine Program, Northridge, CA 91325, USA.

出版信息

Evid Based Complement Alternat Med. 2013;2013:238454. doi: 10.1155/2013/238454. Epub 2013 Nov 28.

Abstract

Background. SuperUlam is a proprietary blend of natural ingredients aimed at supporting brain health. We aimed to evaluate the effect of SuperUlam on attention and mood in healthy adults. Methods. Twenty healthy individuals aged 35-65 were enrolled in this randomized, double-blind, placebo-controlled, crossover study. Study duration was 3 weeks and consisted of 3 visits. Measurement of cognitive function included computer-based testing of reaction time, complex attention, working memory, sustained attention, and executive functioning. Mood testing was performed via the profile of mood states (POMS) survey and the Chalder fatigue scale. Results. Cognitive function testing demonstrated a significant improvement from baseline in executive functioning, cognitive flexibility, reaction time, and working memory in the product group only (P < 0.05). When comparing the study product to placebo, the data demonstrated a significant decrease in tension, depression, and anger (P < 0.05). There was no significant difference between the product and placebo in the other measures of mood, including vigor, fatigue, confusion, and total mood disturbance. No adverse events were reported. Conclusions. Supplementation with SuperUlam is safe to consume with potential benefits to cognitive function and mood.

摘要

背景

SuperUlam 是一种专有的天然成分混合物,旨在支持大脑健康。我们旨在评估 SuperUlam 对健康成年人注意力和情绪的影响。

方法

20 名年龄在 35-65 岁的健康成年人参与了这项随机、双盲、安慰剂对照、交叉研究。研究持续 3 周,包括 3 次就诊。认知功能的测量包括基于计算机的反应时间、复杂注意力、工作记忆、持续注意力和执行功能测试。情绪测试通过心境状态问卷(POMS)和 Chalder 疲劳量表进行。

结果

认知功能测试显示,仅在产品组中,执行功能、认知灵活性、反应时间和工作记忆从基线开始就有显著改善(P < 0.05)。与安慰剂相比,数据显示在紧张、抑郁和愤怒方面有显著降低(P < 0.05)。在其他情绪衡量指标(包括活力、疲劳、困惑和总体情绪困扰)方面,产品与安慰剂之间没有显著差异。没有报告不良反应。

结论

补充 SuperUlam 是安全的,并且可能对认知功能和情绪有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab30/3863557/fb52c77a9caa/ECAM2013-238454.001.jpg

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