Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, 45276 Essen, Germany.
Department of General Oncology and the Integrative Medicine Program, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Evid Based Complement Alternat Med. 2013;2013:383142. doi: 10.1155/2013/383142. Epub 2013 Nov 27.
More and more cancer patients use complementary therapies. As the majority of patients do not disclose their use of complementary therapies to their oncologists, they expose themselves to possible detrimental effects from the therapies due to drug interactions. To meet the needs of patients and health care professionals on valid information on complementary therapies, the collaborative research project "Competence Network Complementary Medicine in Oncology-KOKON", an interdisciplinary network for complementary medicine research in oncology, was established. Moreover, Integrative Oncology, a combination of conventional and evidenced-based complementary therapies delivered using a comprehensive approach, is now increasingly used in the United States and Europe. A variety of different Integrative Oncology models have been established worldwide including an expert-based model at the Kliniken Essen-Mitte, Essen, Germany and a patient-centered, evidenced-based approach at The University of Texas MD Anderson Cancer Center. Both models are briefly reviewed. More research is needed and Comparative Effectiveness Research that places strong emphasis on the comparison of different treatment options in usual care settings by including more heterogeneous patients, using less standardized treatment protocols, and measuring patient-centered outcomes would provide useful information for decision-making. To improve the quality of care and research in Integrative Oncology, sustainable financial models for Integrative Oncology and more funding for research are needed.
越来越多的癌症患者使用补充疗法。由于大多数患者没有向肿瘤医生透露他们使用补充疗法的情况，因此他们可能会因药物相互作用而暴露在这些疗法的潜在有害影响之下。为了满足患者和医疗保健专业人员对补充疗法的有效信息的需求，成立了合作研究项目“肿瘤学补充医学协作网络-KOKON”，这是一个肿瘤学补充医学研究的跨学科网络。此外，综合肿瘤学，即常规和基于证据的补充疗法的结合，采用综合方法进行治疗，目前在美国和欧洲越来越多地使用。全世界已经建立了各种不同的综合肿瘤学模式，包括德国埃森中部 Kliniken Essen 的基于专家的模式和德克萨斯大学 MD 安德森癌症中心的以患者为中心、基于证据的方法。这两种模式都进行了简要回顾。需要开展更多的研究，需要开展更强调在常规治疗环境中比较不同治疗选择的比较效果研究，包括更具异质性的患者，使用不太标准化的治疗方案，并测量以患者为中心的结果，这将为决策提供有用的信息。为了提高综合肿瘤学的护理和研究质量，需要可持续的综合肿瘤学财务模式和更多的研究资金。
