Jabbari Nasrollah, Barati Amir Hoshang, Rahmatnezhad Leili
Department of Medical Physics and Imaging, Urmia University of Medical Sciences, Urmia, Iran.
Department of Medical Physics, Kurdistan University of Medical Sciences, Sannandaj, Iran.
Rep Pract Oncol Radiother. 2012 May 30;17(4):211-9. doi: 10.1016/j.rpor.2012.04.003. eCollection 2012.
The aim of this work was to develop multiple-source models for electron beams of the NEPTUN 10PC medical linear accelerator using the BEAMDP computer code.
One of the most accurate techniques of radiotherapy dose calculation is the Monte Carlo (MC) simulation of radiation transport, which requires detailed information of the beam in the form of a phase-space file. The computing time required to simulate the beam data and obtain phase-space files from a clinical accelerator is significant. Calculation of dose distributions using multiple-source models is an alternative method to phase-space data as direct input to the dose calculation system.
Monte Carlo simulation of accelerator head was done in which a record was kept of the particle phase-space regarding the details of the particle history. Multiple-source models were built from the phase-space files of Monte Carlo simulations. These simplified beam models were used to generate Monte Carlo dose calculations and to compare those calculations with phase-space data for electron beams.
Comparison of the measured and calculated dose distributions using the phase-space files and multiple-source models for three electron beam energies showed that the measured and calculated values match well each other throughout the curves.
It was found that dose distributions calculated using both the multiple-source models and the phase-space data agree within 1.3%, demonstrating that the models can be used for dosimetry research purposes and dose calculations in radiotherapy.
本研究旨在使用BEAMDP计算机代码为NEPTUN 10PC医用直线加速器的电子束开发多源模型。
放射治疗剂量计算最精确的技术之一是辐射传输的蒙特卡罗(MC)模拟,这需要以相空间文件的形式提供射束的详细信息。从临床加速器模拟射束数据并获取相空间文件所需的计算时间很长。使用多源模型计算剂量分布是一种替代方法,可将相空间数据作为直接输入到剂量计算系统中。
对加速器头部进行蒙特卡罗模拟,记录有关粒子历史细节的粒子相空间。从蒙特卡罗模拟的相空间文件构建多源模型。这些简化的射束模型用于生成蒙特卡罗剂量计算,并将这些计算结果与电子束的相空间数据进行比较。
使用相空间文件和多源模型对三种电子束能量的测量和计算剂量分布进行比较,结果表明测量值和计算值在整个曲线上相互匹配良好。
发现使用多源模型和相空间数据计算的剂量分布在1.3%以内一致,表明这些模型可用于放射治疗中的剂量学研究目的和剂量计算。