Demir Mehmet, Guven Dilek, Koc Arzu, Ozdemir Savas, Can Efe
Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
Department of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, Turkey.
J Ophthalmol. 2013;2013:752186. doi: 10.1155/2013/752186. Epub 2013 Nov 26.
Aim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion cell complex (GCC) thicknesses were measured by optical coherence tomography (OCT). In addition, visual acuity (VA), intraocular pressure (IOP), refractive errors, central macular thickness (CMT), central corneal thickness (CCT), and excavation of optic disc were evaluated in all subjects. Results. Mean values of GCC, IOP, VA, CMT, CCT, and refractive errors were similar between the 2 groups. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses were higher in subjects with PCOS than in healthy subjects (P = 0.003, P = 0.012, and P = 0.009), respectively. Conclusion. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses in women with PCOS were significantly higher than in healthy women.
目的。比较多囊卵巢综合征（PCOS）女性与健康女性的视网膜神经纤维层（RNFL）厚度。材料与方法。该研究纳入了44例PCOS女性的88只眼（第1组）和42例健康女性的84只眼（第2组）。对所有受试者，采用光学相干断层扫描（OCT）测量RNFL和神经节细胞复合体（GCC）厚度。此外，对所有受试者评估视力（VA）、眼压（IOP）、屈光不正、中心黄斑厚度（CMT）、中央角膜厚度（CCT）和视盘凹陷。结果。两组之间GCC、IOP、VA、CMT、CCT和屈光不正的平均值相似。PCOS受试者的平均RNFL、上方平均RNFL和下方平均RNFL厚度分别高于健康受试者（P = 0.003、P = 0.012和P = 0.009）。结论。PCOS女性的平均RNFL、上方平均RNFL和下方平均RNFL厚度显著高于健康女性。
