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人乳比婴儿配方奶粉具有更好的抗氧化能力。

Human breast milk provides better antioxidant capacity than infant formula.

作者信息

Oveisi Mohammad Reza, Sadeghi Naficeh, Jannat Behrooz, Hajimahmoodi Mannan, Behfar Abd-Ol-Azim, Jannat Forouzandeh, Mokhtarinasab Fariba

机构信息

Department of Drug and Food Control, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Food and Drug Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran.

出版信息

Iran J Pharm Res. 2010 Fall;9(4):445-9.

Abstract

Human milk contains all of the constituents that are required for the optimal growth and development of a neonate. It supports the development of brain, immune, and physiological systems. This study aimed to consider the significance of breast milk in preventing oxidative stress by comparing total antioxidant capacity (TAC) in breast and formula milk for premature infants, demonstrating the relationship between TAC in breast milk and postnatal age in days. The Ferric reducing antioxidant power assay (FRAP) method was used to spectophotometrically measure of TAC in breast and formula milk. One hundred and fourty (n = 140) lactating mothers agreed to participate in the study. TAC was also measured in two brands of formula milk (n = 80). The Range of TAC in human breast milk was 234.27-1442.31 μM and in two formula was 160.04-630.92 μM. The average TAC was significantly higher in breast milk (642.94 ± 241.23 μM) compared to formula milk (280.986 ± 100.34 μM) p < 0.0001. The TAC of breast milk was increased with some nutritional parameter such as increased consumption of cheese, vegetables, fruits, bread and nuts. Infants' height at the birthday was directly correlated with antioxidant capacity of breast milk, whilst a reversed correlation was observed between TAC in breast milk and infant age. Based on our results, it is concluded that the TAC of breast milk is varied and affected by nutrition. It is alo observed that TAC is significantly higher in breast milk than formula, which means that breast milk provides better antioxidant potency than infant formula.

摘要

母乳含有新生儿最佳生长发育所需的所有成分。它支持大脑、免疫和生理系统的发育。本研究旨在通过比较早产儿母乳和配方奶中的总抗氧化能力(TAC),探讨母乳在预防氧化应激方面的意义,证明母乳中TAC与出生后天数之间的关系。采用铁还原抗氧化能力测定法(FRAP)分光光度法测量母乳和配方奶中的TAC。140名哺乳期母亲同意参与该研究。还对两个品牌的配方奶(n = 80)进行了TAC测量。人母乳中TAC的范围为234.27 - 1442.31μM,两种配方奶中为160.04 - 630.92μM。与配方奶(280.986±100.34μM)相比,母乳中的平均TAC显著更高(642.94±241.23μM),p < 0.0001。母乳中的TAC会随着一些营养参数的增加而升高,如奶酪、蔬菜、水果、面包和坚果摄入量的增加。婴儿周岁时的身高与母乳的抗氧化能力直接相关,而母乳中的TAC与婴儿年龄呈负相关。根据我们的研究结果,得出结论:母乳中的TAC会因营养而有所变化并受到影响。还观察到母乳中的TAC显著高于配方奶,这意味着母乳比婴儿配方奶具有更好的抗氧化能力。

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