Kotowski Jacek, Wollstein Gadi, Ishikawa Hiroshi, Schuman Joel S
Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Surv Ophthalmol. 2014 Jul-Aug;59(4):458-67. doi: 10.1016/j.survophthal.2013.04.007. Epub 2013 Oct 16.
Because glaucomatous damage is irreversible early detection of structural changes in the optic nerve head and retinal nerve fiber layer is imperative for timely diagnosis of glaucoma and monitoring of its progression. Significant improvements in ocular imaging have been made in recent years. Imaging techniques such as optical coherence tomography, scanning laser polarimetry and confocal scanning laser ophthalmoscopy rely on different properties of light to provide objective structural assessment of the optic nerve head, retinal nerve fiber layer and macula. In this review, we discuss the capabilities of these imaging modalities pertinent for diagnosis of glaucoma and detection of progressive glaucomatous damage and provide a review of the current knowledge on the clinical performance of these technologies.
由于青光眼性损害是不可逆的,因此对视神经乳头和视网膜神经纤维层的结构变化进行早期检测,对于青光眼的及时诊断及其病情进展监测至关重要。近年来,眼部成像技术取得了显著进展。光学相干断层扫描、扫描激光偏振仪和共焦扫描激光检眼镜等成像技术利用光的不同特性,对视神经乳头、视网膜神经纤维层和黄斑进行客观的结构评估。在本综述中,我们讨论了这些成像方式在青光眼诊断和青光眼性进行性损害检测方面的能力,并对这些技术的临床性能的现有知识进行了综述。