Ercan Suleyman, Davutoglu Vedat, Altunbas Gokhan, Inanc Ibrahim Halil, Kaplan Mehmet, Oylumlu Muhammed, Koç Ibrahim, Yuce Murat, Ozer Orhan, Soydinc Serdar
Department of Cardiology, University of Gaziantep, Gaziantep, Turkey.
Clin Cardiol. 2014 Feb;37(2):115-8. doi: 10.1002/clc.22239. Epub 2014 Jan 7.
The purpose of this study was to determine the long-term prognostic implications of incidental pleural effusion (PE) detected during echocardiographic examination and its relationship with concomitant diseases.
The study hypothesis is to test whether incidental pleural PE detected during echocardiographic examination be used as a prognostic marker.
The study was performed by evaluating patient records (N = 251) in whom PE was incidentally detected during echocardiographic examination in a tertiary hospital between 1999 and 2012. The patients were classified into 4 major groups according to the concomitant primary disease: malignancy, and cardiovascular, renal, and pulmonary diseases. The total survival time was obtained from hospital records for patients who died during the hospital stay and social security institution records for patients with out-of-hospital death.
One-year and 5-year life expectancies of PE cases concomitant with different disorders were as follows; heart failure (n = 151), 81% and 70%; malignancies (n = 45), 53% and 44%; pulmonary diseases (n = 37), 89% and 78%; renal diseases (n = 18), 100% and 83%; respectively. PE associated with heart failure, renal disease, and pulmonary disease had similar (P > 0.05 for all) and favorable outcomes compared to PE associated with malignancies (P < 0.001).
The prognosis of incidental PE was the worst in patients with concomitant malignancies; however, PE associated with nonmalignant diseases including heart failure, pulmonary disease, and renal disease have similar and favorable outcomes.
本研究旨在确定超声心动图检查时发现的偶然胸腔积液（PE）的长期预后意义及其与伴发疾病的关系。
本研究假设是检验超声心动图检查时发现的偶然胸腔PE是否可作为预后标志物。
本研究通过评估1999年至2012年在一家三级医院超声心动图检查时偶然发现PE的患者记录（N = 251）进行。根据伴发的原发性疾病，将患者分为4个主要组：恶性肿瘤、心血管疾病、肾脏疾病和肺部疾病。从住院期间死亡患者的医院记录和院外死亡患者的社会保障机构记录中获取总生存时间。
伴有不同疾病的PE病例的1年和5年预期寿命如下：心力衰竭（n = 151），分别为81%和70%；恶性肿瘤（n = 45），分别为53%和44%；肺部疾病（n = 37），分别为89%和78%；肾脏疾病（n = 18），分别为100%和83%。与恶性肿瘤相关的PE相比，与心力衰竭、肾脏疾病和肺部疾病相关的PE具有相似（所有P > 0.感5）且良好的预后（P < 0.001）。
伴有恶性肿瘤的患者中偶然PE的预后最差；然而，与包括心力衰竭、肺部疾病和肾脏疾病在内的非恶性疾病相关的PE具有相似且良好的预后。
