Kang Hyun Wook
Department of Biomedical Engineering, Pukyong National University, 45 Yongso-ro, Nam-gu, Busan, 608-737, South Korea,
Lasers Med Sci. 2014 Jan;29(1):273-7. doi: 10.1007/s10103-013-1325-2. Epub 2013 Apr 30.
Laser light has been widely used as a surgical tool to treat benign prostate hyperplasia (BPH). Various surgical parameters still need to be tested and optimized to accomplish better clinical outcomes. The purpose of the current study is to investigate the effect of fiber core size on ablation performance at various laser power levels. Three optical fibers (600, 775, and 850 μm) were tested in vitro with a customized 532-nm laser system with power ranging from 120 to 180 W. Ablation performance was evaluated in light of total energy, irradiance, and volumetric energy density. Irrespective fiber size, crater dimension, and ablation volume linearly increased with the incident irradiance. However, each fiber created different geometry of ablation craters (i.e., deep columnar shape for 600 μm vs. shallow funnel shape for 850 μm). Smaller fiber size demonstrated the efficient energy usage for tissue removal. In-depth comprehension of fiber performance can help accomplish predictable and efficient surgical procedures for BPH therapy.
激光已被广泛用作治疗良性前列腺增生（BPH）的手术工具。仍需测试和优化各种手术参数以获得更好的临床效果。本研究的目的是研究光纤芯径在不同激光功率水平下对消融性能的影响。使用定制的532纳米激光系统在体外测试了三根光纤（600、775和850微米），功率范围为120至180瓦。根据总能量、辐照度和体积能量密度评估消融性能。无论光纤尺寸如何，弹坑尺寸和消融体积均随入射辐照度线性增加。然而，每根光纤产生的消融弹坑几何形状不同（即600微米的为深柱状，而850微米的为浅漏斗状）。较小的光纤尺寸显示出用于组织切除的能量利用效率更高。深入了解光纤性能有助于实现可预测且高效的BPH治疗手术程序。
